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Exosome-mediated horizontal gene transfer occurs in double-strand break repair during genome editing.
Posted 3 years and 8 months ago

Prevalence of Mutation-Prone Microhomology-Mediated End Joining in a Chordate Lacking the c-NHEJ DNA Repair Pathway.
Posted 6 years and 6 months ago

Nucleosomes Inhibit Cas9 Endonuclease Activity in Vitro.
Posted 6 years and 7 months ago

Multiplexed precision genome editing with trackable genomic barcodes in yeast.
Posted 6 years and 11 months ago

Genome-scale engineering of Saccharomyces cerevisiae with single-nucleotide precision.
Posted 6 years and 11 months ago

CRISPR-Cas12a target binding unleashes indiscriminate single-stranded DNase activity.
Posted 7 years ago

Evolved Cas9 variants with broad PAM compatibility and high DNA specificity.
Posted 7 years and 1 month ago

Precise Cas9 targeting enables genomic mutation prevention.
Posted 7 years and 1 month ago

Transcription-coupled changes in nuclear mobility of mammalian cis-regulatory elements.
Posted 7 years and 2 months ago

CRISPR-Cas encoding of a digital movie into the genomes of a population of living bacteria.
Posted 7 years and 9 months ago