Dai J, Boeke JD, Luo Z, Jiang S, Cai Y.

Genome Biol. 2020 Aug 13;21(1):205. doi:10.1186/s13059-020-02130-z

Sc3.0: revamping and minimizing the yeast genome

Proposes to build a core “essential gene array (eArray)” as a centromeric chromosome that can be linearised to serve as a base to build more complex genomes.