Chez Charles/ biblio/ Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2A.Z-containing nucleosomes.

Genome Res. 2019 May 16. pii: gr.243139.118. doi:10.1101/gr.243139.118

Cakiroglu A, Clapier CR, Ehrensberger AH, Darbo E, Cairns BR, Luscombe NM, Svejstrup J.

Genome-wide reconstitution of chromatin transactions reveals that RSC preferentially disrupts H2A.Z-containing nucleosomes.

H2A.Z-containing nucleosomes are preferentially found at TSSes. The RSC can exert its action on single mononucleosomes: it does not need more context.