In Vitro Cell Dev Biol Anim. 2019 Mar;55(3):149-158. doi:10.1007/s11626-018-00317-0

Munroe S, Sandoval K, Martens DE, Sipkema D, Pomponi SA.

Genetic algorithm as an optimization tool for the development of sponge cell culture media

4 generations of 30 experiments each screening the concentrations of all amino acids.