Nucleic Acids Res. 2004 Feb 18;32(3):e37. doi:10.1093/nar/gnh031

Zhulidov PA, Bogdanova EA, Shcheglov AS, Vagner LL, Khaspekov GL, Kozhemyako VB, Matz MV, Meleshkevitch E, Moroz LL, Lukyanov SA, Shagin DA.

Simple cDNA normalization using kamchatka crab duplex-specific nuclease.

cDNAs substracted by their former templates. DNS cleaves DNA from DNA/RNA duplexes, leaving RNA molecules intact. This would suggest the strong reduction of abundant transcripts.