Power law in high-throughput biology

(very parcellar; work in progress).

Reverse-cumulative distribution of SAGE tags was shown by Kuznetstov, Knott & Bonner (2002) to follow a power law. Balwierz et al., 2009 showed the same for CAGE tags and and implemented a normalisation method fitting the data to the power law.

Power laws are also seen in other areas, for instance in parameters describing network topologies (Barabási & Albert, 1999, Serafino and coll., 2021).

Methods for analyzing deep sequencing expression data: constructing the human and mouse promoterome with deepCAGE data.

Balwierz PJ, Carninci P, Daub CO, Kawai J, Hayashizaki Y, Van Belle W, Beisel C, van Nimwegen E.

Genome Biol. 2009;10(7):R79. doi:10.1186/gb-2009-10-7-r79

Methods for analyzing deep sequencing expression data: constructing the human and mouse promoterome with deepCAGE data.

Power-law normalisation for CAGE.