Adenylylation
Adenylylation is the addition of an AMP moiety to a phosphorylated end. In vitro, it is performed by ligases. See the ligase tag for details.
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Archaeal RNA ligase is a homodimeric protein that catalyzes intramolecular ligation of single-stranded RNA and DNA.
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Synthesis of adenylated RNA. ssNpR(A) are good acceptors. pCpN are good donors.
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Donor activation in the T4 RNA ligase reaction.
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