Arash Farhadi, Gabrielle H. Ho, Daniel P. Sawyer, Raymond W. Bourdeau, Mikhail G. Shapiro

Science 27 Sep 2019 Vol. 365, Issue 6460, pp. 1469-1475 doi:10.1126/science.aax4804

Ultrasound imaging of gene expression in mammalian cells

Bacillus megaterium gas vesicle genes were codon-optimised and transfected into mammalian cells. What is detected is the collapse of the gas vesicles under ultrasound exposure.