Nenarokova A, Záhonová K, Krasilnikova M, Gahura O, McCulloch R, Zíková A, Yurchenko V, Lukeš J.

mBio. 2019 Jul 16;10(4):e01541-19. doi:10.1128/mBio.01541-19

Causes and Effects of Loss of Classical Nonhomologous End Joining Pathway in Parasitic Eukaryotes.

Reviews possible advantages of losing the C-NHEJ pathway, such as reduction of transposon movement, reduction of genome size and change of genome structure, and insertion of short new sequence in proteins. Focus on parasites but some facts about Oikopleura are highlighted for comparison purposes.