Coppola U, Ristoratore F, Albalat R, D'Aniello S.

Cell Mol Life Sci. 2019 Apr 26. doi:10.1007/s00018-019-03103-7

The evolutionary landscape of the Rab family in chordates.

“O. dioica lineage showed 11 additional losses, Rab4, Rab7L1, Rab9, Rab19/43, Rab21 Rab26/37, Rab28, Ift27, Rasef, EFcab4/Rab44 and RabX1. This species has, therefore, lost almost the 50% of the Rab toolkit, being the metazoan species with the smallest number of Rab subfamilies described so far.” “We detected [...] 5 independent duplications in O. dioica (Rab5/17, Rab6, Rab7, Rab10, Rab35).” O. dioica lost the Rab-EF chimeras Rasef and EFcab4/44, but kept Rab46.