Garrison E, Sirén J, Novak AM, Hickey G, Eizenga JM, Dawson ET, Jones W, Garg S, Markello C, Lin MF, Paten B, Durbin R.

Nat Biotechnol. 2018 Oct;36(9):875-879. doi:10.1038/nbt.4227

Variation graph toolkit improves read mapping by representing genetic variation in the reference.

“Using the vg toolkit, we can construct or import a graph, modify it, visualize it, and use it as a reference.”