Zhong Z, Zhai Y, Bu P, Shah S, Qiao L.

Nat Commun. 2017 Apr 11;8:15004. doi:10.1038/ncomms15004.

Papilloma-pseudovirus eradicates intestinal tumours and triples the lifespan of Apc(Min/+) mice.

HPV pseudoviruses have tropsim for cancer cells (other cells in this system do not express the needed heparan sulfate proteoglycains in the needed conformation). Capsid and (non-replicative plasmid) DNA activate innate immunity against the infected cancer cells.