Martí-Solans J, Belyaeva OV, Torres-Aguila NP, Kedishvili NY, Albalat R, Cañestro C.

Mol Biol Evol. 2016 Sep;33(9):2401-16. doi:10.1093/molbev/msw118

Coelimination and Survival in Gene Network Evolution: Dismantling the RA-Signaling in a Chordate.

Some genes are lost (Aldh1a, Cyp26, Rdh10, Rdh16, and Bco1) and others show signs of neofunctionalisation (RdhE2, Aldh8a1). “O. dioica did not contain atRA at concentrations that were likely to play any role in developmental or physiological processes.”