Arnaud O, Kato S, Poulain S, Plessy C.

Biotechniques. 2016 Apr 1;60(4):169-74. doi:10.2144/000114400

Targeted reduction of highly abundant transcripts using pseudo-random primers.

Reduction of rRNA or hemoglobin with as few as 40 primers, while keepign whole-transcriptome coverage, at the cost of as systematic bias.