PLoS Comput Biol. 2014 Jul 17;10(7):e1003696. doi:10.1371/journal.pcbi.1003696

McDavid A, Dennis L, Danaher P, Finak G, Krouse M, Wang A, Webster P, Beechem J, Gottardo R

Modeling bi-modality improves characterization of cell cycle on gene expression in single cells.

333 genes studied in 930 cells with the Hurdle model. Nanostring technology. “the cell cycle explains only 5%-17% of expression variability”