O'Duibhir E, Lijnzaad P, Benschop JJ, Lenstra TL, van Leenen D, Groot Koerkamp MJ, Margaritis T, Brok MO, Kemmeren P, Holstege FC

Mol Syst Biol. 2014 Jun 21;10:732. doi:10.15252/msb.20145172

Cell cycle population effects in perturbation studies.

The slow growth / environmental stress response signature is to a large extent caused by a shift in cell cycle distribution. Removal of this signature enhances the specific effects of perturbations on transcript expression levels.