Liang H, Esposito A, De S, Ber S, Collin P, Surana U, Venkitaraman AR.

Nat Commun. 2014 Jun 4;5:4048. doi:10.1038/ncomms5048

Homeostatic control of polo-like kinase-1 engenders non-genetic heterogeneity in G2 checkpoint fidelity and timing.

Cells overcome the G2 checkpoint after accumulating PLK1 activity even if double-strand breaks remain.