Cisse II, Izeddin I, Causse SZ, Boudarene L, Senecal A, Muresan L, Dugast-Darzacq C, Hajj B, Dahan M, Darzacq X.

Real-time dynamics of RNA polymerase II clustering in live human cells.

Short half-life support de novo self-organisation. Inhibition of P-TEFb by flavopiridol stabilises the clusters, suggesting they are made of pre-initiation or pre-elongation complexes.