Kwak H, Fuda NJ, Core LJ, Lis JT.

Science. 2013 Feb 22;339(6122):950-3. doi: 10.1126/science.1229386.

Precise maps of RNA polymerase reveal how promoters direct initiation and pausing.

PRO-seq and PRO-cap (based on oligo-capping). Incorporation of biotin-NTPs cause the polymerase to stop, thus brings single-nucleotide resolution.