Dadiani M, van Dijk D, Segal B, Field Y, Ben-Artzi G, Raveh-Sadka T, Levo M, Kaplow I, Weinberger A, Segal E.

Genome Res. 2013 May 1.

Two DNA-encoded strategies for increasing expression with opposing effects on promoter dynamics and transcriptional noise.

Increasing promoter accessibility increases the rate of activation; increasing the strength of transcription factor binding sites reduce the rate of inactivation.