Chez Charles/ biblio/ Sequestration of highly expressed mRNAs in cytoplasmic granules, P-bodies, and stress granules enhances cell viability.

Lavut A, Raveh D.

PLoS Genet. 2012 Feb;8(2):e1002527. Epub 2012 Feb 23.

Sequestration of highly expressed mRNAs in cytoplasmic granules, P-bodies, and stress granules enhances cell viability.

Direct transport of transcribed RNA to granlues can also account to the discreapancy between RNA and protein counts. Cells unable to localise RNA to granules are more sensitive to gene overexpression.