PLoS One. 2007 Feb 14;2(2):e197.
Binladen J, Gilbert MT, Bollback JP, Panitz F, Bendixen C, Nielsen R, Willerslev E.
The use of coded PCR primers enables high-throughput sequencing of multiple homolog amplification products by 454 parallel sequencing.
There is a bias that might be caused by some sequence-specificity of the DNA ligase.