Ganova-Raeva L, Zhang X, Cao F, Fields H, Khudyakov Y.

Nucleic Acids Res. 2006 Jun 21;34(11):e76. doi: 10.1093/nar/gkl391

Primer Extension Enrichment Reaction (PEER): A New Subtraction Method for Identification of Genetic Differences Between Biological Specimens

Generates primers by MmeI cleavage of cDNA extremities, and inactivates those which are complementary to the driver library by extending them with ddNTP