Nucleic Acids Res. 2004 Jun 17;32(11):e86 doi:10.1093/nar/gnh085

Cole K, Truong V, Barone D, McGall G.

Direct labeling of RNA with multiple biotins allows sensitive expression profiling of acute leukemia class predictor genes.

T4 RNA ligase reaction efficiency improved by PEG and pre-adenylation. Direct labelling method for big quantities: RNA fragmentation, then T4 RNA ligation of biotinylated oligos.