Rocha, Eduardo P C.

Trends Genet. 2003 Nov;19(11):600-3. doi:10.1016/j.tig.2003.09.011

DNA repeats lead to the accelerated loss of gene order in bacteria.

Defines a Gene Order Conservation (GOC) number as: “the average number of orthologues for which the consecutive orthologue co-occurs close by in the other genome. It varies between 0 (no co-occurrence) and 1 (complete gene order conservation)”.