Ozbudak EM, Thattai M, Kurtser I, Grossman AD, van Oudenaarden A.

Nat Genet. 2002 May;31(1):69-73. Epub 2002 Apr 22.

Regulation of noise in the expression of a single gene.

Transcription and translation rates varied by point mutations in reporters. Suboptimal translation rates naturally exist in some genes and may be selected for their effect of reducing noise caused by transcription bursts.