David Lagman, Anthony Leon, Nadia Cieminska, Wei Deng, Marios Chatzigeorgiou, Simon Henriet, Daniel Chourrout

bioRxiv 2023.07.18.549157; doi:10.1101/2023.07.18.549157

Pax37 gene function in Oikopleura dioica supports a neuroepithelial-like origin for its house-making Fol territory

Knock-out of Pax37B and Pax37A using CRISPR-Cas9. Pax37B is essential to the proper patterning of the oikoblastic epithelium but not Pax37A. Based on the analysis of single-cell and transcriptomic data in Oikopleura and Ciona, the authors propose a parallel between oikoblastic cells in Oikopleura and the neuroepithelial cells that produce gluing collocytes in Ciona.